Jesse Eisenberg

Simon James / James Simon

Mia Wasikowska

Hannah

Wallace Shawn

Mr. Papadopoulos

Yasmin Paige

Melanie

Noah Taylor

Harris

James Fox

The Colonel

Cathy Moriarty

Kiki

Phyllis Somerville

Simon's Mother

Gabrielle Downey

Strange Woman

Jon Korkes

Detective

Craig Roberts

Young Detective

Kobna Holdbrook-Smith

Guard / Doctor

Susan Blommaert

Liz

Bruce Byron

Skinhead

J. Mascis

Janitor