Samuel L. Jackson

Afro / Ninja-Ninja (voice)

Lucy Liu

Sio (voice)

Yuri Lowenthal

Jinno (voice)

Mark Hamill

Bin / Oden Shop Master (voice)

Jeff Bennett

Brother 3 (voice)

S. Scott Bullock

Professor Dharman / Kidnapper (voice)

Grey DeLisle

Tomoe / Ogin (voice)

Greg Eagles

Afro's Father (voice)

Zachary Gordon

Kotaro (voice)

Liam O'Brien

Shichogoro (voice)

RZA

DJ (voice)

Phil LaMarr

Young Afro (voice)

Ariel Winter

Young Sio (voice)

Kevin Michael Richardson

Blacksmith / Takimoto (voice)

Steve Blum

Man A / Assassins (voice)