Marg Helgenberger

Hannah Montgomery

Betty Gilpin

Gloria Mitchell

Henry Lau

Trent

Kathryn Prescott

Clarity June "CJ" Mitchell

Dennis Quaid

Ethan Montgomery

Josh Gad

Bailey / Molly / Big Dog / Max (voice)

Abby Ryder Fortson

Young CJ

Emma Volk

Toddler CJ

Ian Chen

Young Trent

Jake Manley

Shane

Johnny Galecki

Henry Montgomery

Tyler Asher Xin-Qin

Saint

Beckett Richard Pin

15-Month-Old Saint

Daniela Barbosa

Liesl

Kevin Claydon

Barry