Jason Segel

Gary

Amy Adams

Mary

Chris Cooper

Tex Richman

Rashida Jones

CDE Executive

Steve Whitmire

Kermit / Beaker / Statler / Rizzo / Link / Newsman (voice)

Peter Linz

Walter (voice)

Eric Jacobson

Miss Piggy / Fozzie / Animal / Sam Eagle / Marvin Suggs (voice)

Dave Goelz

Gonzo / Honeydew / Zoot / Beauregard / Waldorf (voice)

Bill Barretta

Swedish Chef / Rowlf / Teeth / Pepe / Bobo / Muppet Gary (voice)

David Rudman

Scooter / Janice / Miss Poogy / Wayne (voice)

Matt Vogel

Pepper / Camilla / Sweetums / Robot / Deadly / Harry (voice)

Alan Arkin

Tour Guide

Bill Cobbs

Grandfather

Zach Galifianakis

Hobo Joe

Ken Jeong

Punch Teacher Host