Steve Carell

Gru (voice)

Jason Segel

Vector (voice)

Russell Brand

Dr Nefario (voice)

Miranda Cosgrove

Margo (voice)

Dana Gaier Ellis

Edith (voice)

Elsie Fisher

Agnes (voice)

Pierre Coffin

Tim the Minion / Bob the Minion / Mark the Minion / Phil the Minion / Stuart the Minion (voice)

Julie Andrews

Gru's Mom (voice)

Will Arnett

Mr. Perkins (voice)

Kristen Wiig

Miss Hattie (voice)

Chris Renaud

Dave the Minion (voice)

Jemaine Clement

Jerry the Minion (voice)

Jack McBrayer

Carnival Barker / Tourist Dad (voice)

Danny McBride

Fred McDade (voice)

Mindy Kaling

Tourist Mom (voice)