Cary Grant

Mortimer Brewster

Priscilla Lane

Elaine Harper Brewster

Josephine Hull

Aunt Abby Brewster

Jean Adair

Aunt Martha Brewster

Raymond Massey

Jonathan Brewster

John Alexander

'Teddy Roosevelt' Brewster

Peter Lorre

Dr. Einstein

Jack Carson

Officer Patrick O'Hara

Edward Everett Horton

Mr. Witherspoon

James Gleason

Lt. Rooney

Grant Mitchell

Reverend Harper

Edward McNamara

Sergeant Brophy

Garry Owen

Taxi Cab Driver

John Ridgely

Officer Saunders

Vaughan Glaser

Judge Cullman