David Byrne

Narrator / Lip-Syncher

John Goodman

Louis Fyne

Annie McEnroe

Kay Culver

Jo Harvey Allen

The Lying Woman

Spalding Gray

Earl Culver

Alix Elias

The Cute Woman

Roebuck 'Pops' Staples

Mr. Tucker

Tito Larriva

Ramon

John Ingle

The Preacher

Matthew Posey

The Computer Guy

Swoosie Kurtz

The Lazy Woman

Amy Buffington

Linda Culver

Richard Dowlearn

Larry Culver

Capucine De Wulf

The Little Girl on the Road

Cynthia Gould

Factory Girl #1