Humphrey Bogart

Samuel Spade

Mary Astor

Brigid O'Shaughnessy

Gladys George

Iva Archer

Peter Lorre

Joel Cairo

Barton MacLane

Lt. of Detectives Dundy

Lee Patrick

Effie Perine

Sydney Greenstreet

Kasper Gutman

Ward Bond

Det. Tom Polhaus

Jerome Cowan

Miles Archer

Elisha Cook Jr.

Wilmer Cook

James Burke

Luke

Murray Alper

Frank Richman

John Hamilton

District Attorney Bryan

Charles Drake

Reporter (uncredited)

Chester Gan

Bit Part (uncredited)